Compare the Top On-Premises Healthcare CRM Software as of April 2026

What is On-Premises Healthcare CRM Software?

Healthcare CRM software helps healthcare providers manage and improve relationships with patients and other stakeholders. These platforms offer tools for patient communication, appointment scheduling, follow-up reminders, and personalized care. Healthcare CRM software also enables patient segmentation, allowing providers to target specific groups with tailored messaging and services. By centralizing patient data, CRM systems make it easier to track patient history, monitor treatment progress, and enhance patient engagement. Additionally, these platforms often integrate with other healthcare systems like Electronic Health Records (EHR) for a seamless experience. Compare and read user reviews of the best On-Premises Healthcare CRM software currently available using the table below. This list is updated regularly.

  • 1
    InfoFlo

    InfoFlo

    InfoFlo Solutions Inc

    Case Management software made simple so you can focus on your non profit. 360 degree views of your cases all from a single dashboard. Get rid of those excel documents and start accessing your data from any anywhere on any device. With InfoFlo you will get a fully customized system to fit your needs all at an affordable price.
    Starting Price: $20/month/user
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  • 2
    Act!

    Act!

    Act!

    Act! Advantage is a full front-office CRM solution with all-new functionality that unites sales, marketing, and customer management in one intuitive, affordable platform to help you stay organized, attract new customers, and turn relationships into results. Act! Advantage includes Interactive Quotes, Website Chat, Accounting Integration, Appointment Scheduling, Project Management, Web Forms, Online Surveys, and more, broadening Act!'s footprint across your entire front office, and reducing your need for costly, third-party tools. Additionally, you can select the perfect fit, cost-effective tier to meet your current needs with peace of mind knowing that Act! will grow with you. For 38 years, Act! has partnered with small and midsize businesses - listening, learning, and building alongside them and Act! Advantage is the culmination of nearly four decades of their feedback. Every feature is designed to reflect how today’s SMBs run their businesses.
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    Starting Price: $30.00/month/user
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  • 3
    Creatio

    Creatio

    Creatio

    Creatio provides a healthcare CRM platform built on its AI-native no-code architecture, enabling healthcare organizations to manage patient relationships and automate clinical and operational workflows within a single system. The platform centralizes patient data, interactions, and care processes, supporting improved coordination and personalized engagement across the patient journey. Creatio enables automation of key healthcare workflows such as patient onboarding, appointment management, communication, and care coordination, while maintaining a 360-degree view of patient data and interactions. It supports integration with critical systems like EHRs, billing platforms, and patient portals, ensuring seamless data exchange and compliance with industry regulations, including HIPAA. At the core of the platform are AI agents that analyze patient and operational data, provide predictive insights, recommend next-best actions, and automate routine processes.
    Starting Price: $25 per user per month
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  • 4
    MEFTiiCOMM

    MEFTiiCOMM

    MEFTiiCOMM

    Introducing MEFTiiCOMM, our comprehensive healthcare communication platform, an all-in-one solution designed to connect doctors, nurses, and managers within or across organizations. With text messaging, audio/video calling, a built-in pager system, and scheduling capabilities, our platform enables seamless communication and collaboration. It is HIPAA compliant, secure, and prevents mixing personal and work communication. Our market-competitive pricing, designed by doctors for healthcare needs, ensures ease of use. Advanced search extends collaboration beyond organizations, facilitating knowledge sharing. Enhance patient care and teamwork with our user-friendly and secure platform.
  • 5
    SpiceCRM

    SpiceCRM

    SpiceCRM

    Being flexible and user-friendly is key to CRM adoption. Not only does SpiceCRM provide a unique user interface but it also adapts the use and the environment and provides a unique user experience. Use it when and in what form you need it. It will adapt to your need and environment. Use it on the Desktop, on the tablet, as a mobile app on iOS or Android. Use it in Outlook or as part of GSuite. Use it with Lotus Notes. And if that is not enough the flexibility will allow you to further adapt it and match your business use cases. Speed matters and is the base to make users love and use a system. All we do focuses on building fast and reliable applications that deliver an outstanding and intuitive user experience. Drive user Adoption and thus data quality and the Value of CRM. Built on open standards this enables you to easily integrate. You will also find resources to support and operate the System since you are not locked into proprietary standards.
    Starting Price: €39 per user and Month
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